Asian Conference on Diarrhoeal Disease and Nutrition (ASCODD)
30 October - 01 November, 2017  |  Kochi, India

    Organized by

    Organizing Institute : RGCBicddr,b
    Partner Institute        : NICEDINCLEN INT
    Sponsors : Bill & Melinda Gates Foundation and others

    Key Persons

    • Professor John D Clemens

      Dr John D Clemens, MD is an expert in vaccine development and evaluation
    • Professor Jan Holmgren

      Dr. Jan Holmgren, MD, PhD is Professor of Medical microbiology and immunology
    • Gordon Dougan, Ph.D.

      Professor Dougan is Senior Group Leader at The Wellcome Trust Sanger Institute.

    • Professor Ann-Mari Svennerholm

      Professor Ann-Mari Svennerholm, M.D., Ph.D, is focusing on Infection and immunity
    • Dr. GB Nair

      Dr. GB Nair, Ph.D, is the Acting Regional Adviser in the Research,
    • Dr. Firdausi Qadri

      Dr. Firdausi Qadri, Ph.D, Senior Director, Infectious Diseases Division, icddr,b.
    • Dr. Tahmeed Ahmed

      Dr. Tahmeed Ahmed, Senior Director, Nutrition & Clinical Services, icddr,b.
    • Professor Niyaz Ahmed

      Dr. Niyaz Ahmed, Senior Director, Laboratory Sciences and Services Division, icddr,b.
    • Dr. Mahfuzur Rahman

      Dr. Mahfuzar Rahman is an epidemiologist with degrees in Medicine and Epidemiology.
    • Professor M Radhakrishna Pillai

      Dr. Pillai’s laboratory's focus is developing fundamental scientific discoveries
    • Prof. Nirmal Kumar Ganguly

      Nirmal Kumar Ganguly, M.D has held several key positions in the Public health space within India and abroad
    • Professor Cecil Czerkinsky

      Cecil Czerkinsky, DMD, Ph.D, Dr. Med Sci, Graduated from Nice and Lyon Medical and
    • Dr. Samuel Mungai Kariuki

      Samuel Mungai Kariuki is Chief Research Scientist and Head of Department,
    • Dr. Martin Mengel

      Dr. Martin Mengel is in charge of AMP's program on enteric diseases.
    • James Michael Fleckenstein

      Associate Professor of Medicine, Washington University School of Medicine.
    • Dr. Sanjay Mehendale

    • Dr. Navin Khanna

      Current research focuses on genetically engineered biomolecules of medical use.


    The abstract submission deadline 

    1st Oct 2017

    Notification of abstract acceptance

    10th Oct 2017

    Early bird registration

    1st Oct 2017

    Late registration

    15th Oct 2017

    Saving Lives – Innovations and solutions for diarrhoeal diseases, enteric fever and malnutrition

    This year's, 14th ASCODD will take place in Kochi, India,  30 October – 01 November, 2017 with the theme of "Saving lives: innovations and solutions for diarrhoeal diseases, enteric fever and malnutrition".  You can expect to interact with the world's leading scientists and researchers.

    We are grateful to Bill & Melinda Gates Foundation for their generous support towards organising ASCODD 2017

    Key Areas at This Year's Conference

    Nutrition (+)

    Session Chair: Dr. Tahmeed Ahmed

    Asia has the highest burden of childhood and maternal malnutrition – both in terms of poor growth and micronutrient deficiencies. This huge burden is associated with diarrheal diseases, again with a very high transmission in this continent. In contrast, overweight and obesity rates are also on the increase and are a cause for concern for what is known as the double burden of malnutrition. In order to be close to the SDG targets for nutrition by 2030, we need to think out of the box, develop and implement innovative interventions targeting the most common and vexing problems of undernutrition. The session on nutrition at this year’s ASCODD will feature state-of-the art lectures and discussion by eminent speakers on maternal nutrition, childhood stunting, environmental enteropathy, and micronutrient deficiencies.

    Microbiota (+)

    Session Chair: Dr. GB Nair

    The human microbiota, collection of microscopic organisms (Archaea, Bacteria and Eukarya) that resides in or on the human body sites, play important role in several aspects of our physiology including assimilation of energy from diet, maturation of immune system, tissue and organ developments and protection against exogenous pathogens. Concurrently, dysbioses, a state of altered microbial ecology, has been linked to a variety of health disorders including inflammatory bowel disease, malnutrition, cardiovascular disease, colon cancer, rheumatoid arthritis, depression, Parkinson's disease and autism spectrum disorder. Understanding a holistic picture of body site-specific microbiomes and identifying 'key' agents/factors of dysbiosis enable individuals to use their expertise.

    Protection against enteric diseases, vaccines and other interventions (+)

    Session Chair: Dr. Firdausi Qadri

    Enteric diseases including diarrhea and enteric fever are a substantial disease burden in developing countries of the world. Better understanding of both the host and the pathogens are key to development of vaccines. Important areas of research in the field are the   mucosal immunology of diseases, understanding of the protective antigens on the pathogens and using these tools to better design efficacious vaccines. Coupled to this is the understanding of  the role of environmental, nutritional  and WaSH factors on the efficacy of vaccines and the immune responses to natural infection and vaccines. Understanding the natural course of immune responses involving innate immunity, adaptive immunity, T and B cell responses, genomic, proteomic and other high throughput methods. In summary, understanding of the genetic and immunological basis of enteric diseases and also the role of available and new vaccines in developing country settings is important. The session on “enteric diseases and vaccines and other interventions” aspires to have key speakers globally to give an update the latest development in the area on enteric diseases and vaccines.

    Gut Immune system and Oral vaccines (+)

    Session Chair: Prof. Ann-Mari Svennerholm

    The session will describe immune responses, with a focus on mucosal immunity, induced by different oral enteric vaccines, e.g. vaccines against cholera, enterotoxigenic E. coli (ETEC) and polio. This includes different approaches to assess mucosal immune responses in the gut such as secretory IgA antibody responses in intestinal lavages and fecal extracts, antibody secreting cells in the circulation as determined by ELISPOT assays or in culture supernatants of such cells (ALS method) and mucosal T cell response. Different approaches to assess induction of immunological memory and homing of circulating B and T cells to the gut as well as efforts to identify immunological markers of protection will also be described. 

    Diarrhoeal Disease Surveillance (+)

    Session Chair: Dr. Sanjukta Sengupta

    Disease surveillance, especially in diarrhoeal and respiratory diseases has been an Achille's heel for most developing countries. Not only is it an expensive proposition to initiate a country-wide routine surveillance activity, there are also issues sustainability and succession, of harmonization of protocols within a network, capacity building & training, the periodic up gradation of equipment, monitoring and dissemination of information about of emerging antibiotic resistance. Sustenance of the surveillance networks and funding available for it, is an issue that needs serious discussion with all the stakeholders. There are also issues of breadth vs depth of a surveillance system that needs to be considered.

    What has been the experience of disease surveillance networks created for typhoid and cholera in Asia and Africa? Are the bottlenecks similar or Region specific? How do countries plan to sustain the activity? Is there funding available with donors or should countries take it on themselves to fund surveillance? How does one communicate the importance of this activity to the respective governments 'as beneficial for their people'? 

    This session will be enriched by experiences and insights along with the usual data sharing. We will have global agencies like GAVI and BMGF to enlighten us as well, on how to improve the evidence base for policy making.

    Point of care diagnostics (+)

    Session Chair: Prof. NK Ganguly

    Diarrhoeal diseases are mostly caused by single pathogens and where they are caused by multiple pathogens, role of each in the causality of the disease is difficult to establish. Routinely only 30-40 % of diarrheal pathogens are detected. However, there are platforms available like TILDA for respiratory pathogens or array based assays e.g. Biofire, which can detect upto more than 26 pathogens within few hours. There are some systems that can identify gut transmitted hepatitis viruses in the market, more are on the anvil.

    Most diarrhoeal diseases are self-treated or in case of children, treated by parents as a part of the normal growth cycle, without proper diagnosis, hence have a chance to lead to antimicrobial resistance. It is therefore important that proper diagnostics tools that are available in the market or being developed are put on the map, just as the ones in the pipeline. Co-morbidities like HIV infection throws up chances of several opportunistic pathogens like cryptosporidia to show up, which also need a proper and timely diagnosis.

    Anti Microbial Resistance (+)

    Session Chair: Dr. Samuel Kariuki

    Antimicrobial resistance has now being recognized as a major global threat to public health. With a number studies from the African region showing worrying trends in multidrug resistance among key bacterial pathogens such as Escherichia coli, Salmonella spp, Staphylococcus aureus, Klebsiella spp and Vibrio cholerae resistant to nearly all commonly available antibiotics, it is imperative that this trend should be reversed. The roll out and implementation of the Global Action Plan to combat antimicrobial resistance will require concerted efforts by all stakeholders through a one health initiative to tackle this problem. Here, we report data on studies in Kenya on AMR and highlight the milestones covered by the country in the drafting and subsequent strategies for implementation of the National action Plan on the Prevention and Containment of Antimicrobial Resistance bacterial pathogens.

    Arsenic and Health (+)

    Session Chair: Dr. Mahfuzur Rahman

    Arsenic has been an issue of major concern in last decades because of the serious impact on human health environmental exposure. Globally, more than 100 million people are at risk with major exposure in Asian countries, including 20 million in Bangladesh alone. Arsenic water contamination is endemic across globe, originated thousands of years ago, when rocks rich in arsenic were eroded and deposited in low lying areas by a natural process. High groundwater extraction for agricultural irrigation and drinking water sources been flagged as a major cause to the problem. A special plenary session of the ASCODD Conference focused on the health effects of exposure to arsenic in drinking water. While it has long been known that arsenic is a human carcinogen, the magnitude of the cancer risk became apparent from studies in Bangladesh and elsewhere. These estimates place arsenic in water as potentially one of the foremost environmental causes of mortality and morbidity in the world today.

    NGS and understanding of enteric pathogens (+)

    Session Chair: Prof. M. Radhakrishna Pillai

    Sequencing of pathogen genomes has significantly improved our understanding on the biology of many enteric pathogens as well as provided better options for identification of novel antibiotic targets. The advent of genome sequencing coupled with advances in bioinformatic analysis to model genome data, promises invaluable insights into bacterial pathogenesis and the design of related therapeutic interventions. Next generation sequencing (NGS) of enteric pathogens is revolutionizing the science in clinical diagnostics, epidemiology and infection genomics. The vast amount of genomic data from enteric pathogens provides a better understanding of virulence traits, adaptability to environments, geographical traceability and transmission to humans, along with a host of other valuable information. The session will provide a better insight on the recent advances in use of NGS data for understanding enteric pathogens and its infection control.

    The conference will once more provide a valuable discussion forum for world experts, all with the joint aim of solving public health problems through innovative scientific research and health care delivery. Join us for the world's leading Diarrhoeal Disease and Nutrition conference. Explore this website for information on the event, uploading your abstract, speaking and exhibiting opportunities.

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